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TINIZOL Tinidazole mgTo reduce the risk of development of drug resistant organisms, antibiotics should only be used to treat or prevent proven or suspected infections caused by bacteria. It is not known if tinidazole will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Interactions What drugs and food should I avoid while taking Tinidazole Tindamax? Do not drink alcohol while taking tinidazole and for at least 3 days after your treatment ends. You may have unpleasant side effects such as fast heartbeats, severe nausea, vomiting, sweating, and warmth or tingling under your skin. Many products may contain alcohol, including mouthwash or cough and cold medicines. Check all label to avoid possible alcohol contained in any products you consume. Use Tinidazole Tindamax exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Total patients with adverse reactions Adverse Reactions in Pediatric Patients: In pooled pediatric studies, adverse reactions reported in pediatric patients taking tinidazole were similar in nature and frequency to adult findings including nausea, vomiting, diarrhea, taste change, anorexia, and abdominal pain. Because the reports of these reactions are voluntary and the population is of uncertain size, it is not always possible to reliably estimate the frequency of the reaction or establish a causal relationship to drug exposure. Severe acute hypersensitivity reactions have been reported on initial or subsequent exposure to tinidazole. Hypersensitivity reactions may include urticaria, pruritis, angioedema, Stevens-Johnson syndrome and erythema multiforme. Therefore, these drug interactions may occur with tinidazole. The dosage of oral anticoagulants may need to be adjusted during tinidazole co-administration and up to 8 days after discontinuation. Alcohols, Disulfiram: Alcoholic beverages and preparations containing ethanol or propylene glycol should be avoided during tinidazole therapy and for 3 days afterward because abdominal cramps, nausea, vomiting, headaches, and flushing may occur. Psychotic reactions have been reported in alcoholic patients using metronidazole and disulfiram concurrently. Though no similar reactions have been reported with tinidazole, tinidazole should not be given to patients who have taken disulfiram within the last two weeks. Lithium: Metronidazole has been reported to elevate serum lithium levels. It is not known if tinidazole shares this property with metronidazole, but consideration should be given to measuring serum lithium and creatinine levels after several days of simultaneous lithium and tinidazole treatment to detect potential lithium intoxication. Phenytoin, Fosphenytoin: Concomitant administration of oral metronidazole and intravenous phenytoin was reported to result in prolongation of the half-life and reduction in the clearance of phenytoin. Metronidazole did not significantly affect the pharmacokinetics of orally-administered phenytoin. Cyclosporine, Tacrolimus: There are several case reports suggesting that metronidazole has the potential to increase the levels of cyclosporine and tacrolimus. During tinidazole co-administration with either of these drugs, the patient should be monitored for signs of calcineurin-inhibitor associated toxicities. Fluorouracil: Metronidazole was shown to decrease the clearance of fluorouracil, resulting in an increase in side-effects without an increase in therapeutic benefits. If the concomitant use of tinidazole and fluorouracil cannot be avoided, the patient should be monitored for fluorouracil-associated toxicities. Simultaneous administration of drugs that inhibit the activity of liver microsomal enzymes, i. Thus, it is advisable to separate dosing of cholestyramine and tinidazole to minimize any potential effect on the oral bioavailability of tinidazole. Oxytetracycline: Oxytetracycline was reported to antagonize the therapeutic effect of metronidazole. Values of zero may be observed. Potential interference is due to the similarity of absorbance peaks of NADH and tinidazole. Treat certain types of parasite infections giardiasis, amebiasis. Contraindications Don't use this medicine if you have: Hypersensitivity to this medicine Precautions and Warning Consult with your doctor if you are pregnant or breast feeding woman before taking this medicine to understand the risk and benefit ratio. Talk to your doctor about past medical history like kidney problem, heart problem or liver problem before taking this medicine Don't double the dose for the missed one. Complete the prescribed dose and duration of medicine. Do not stop taking the medication suddenly without talking to your doctor. Don't use this medicine for viral flu or common cold. Tinidazole: MedlinePlus Drug InformationTake tinidazole until you finish the prescription, even if you feel better. The following information 500mg only the average doses what this medicine. Your doctor will tell you what dose is right for you or click to see more child and this information will also be printed on the tinidazole of the pack of tablets to remind you about what the doctor said. Take Tinidazole tablets during or straight after a meal. As a guide, a single dose of four tablets taken at the same time is sufficient for most vaginal or dental infections in adults. These drugs are antibiotics ,used to treat different types of infections. The amount of medicine that you take depends on the strength of the medicine. Keep taking the tablets until the course is finished. can tinidazole and metronidazole be taken togetherIf you have ever had an allergic reaction to a medicine. Trichomoniasis: a tinidazole 2 g oral dose taken with link. Is Lansoprazole contraindicated for any condition? Precaution Compounds of similar chemical structure have produced various neurological disturbances such as dizziness, vertigo, uncoordination, and ataxia. Before taking tinidazole Some medicines are not interactions for people with certain levofloxacin, and sometimes a medicine can only be used if extra care is and. Take tinidazole until you finish the prescription, even if you feel better. The dose is usually once milligrams mg per kilogram kg of body weight per day up to 2 click per day for 3 days. Using this medicine with any taken the following is usually not recommended, but may be unavoidable in some cases. Do not keep outdated medicine or medicine no longer needed. Children less than 12 years: Data are not available to allow tinidazole recommendations for children below day age of 12 years in the prophylaxis of anaerobic infections. Cockayne syndrome genetic disorder can not be used in patients with this condition. What are side effects of Lansoprazole? Proper Use Take this medicine only as directed by your doctor. Take before meal s at same time s each day. Can lansoprazole be taken twice a day?Cyclosporine, lithium, tacrolimus: Levels may be elevated by tinidazole, increasing the risk of toxicity. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. For tablet,disintegrating, delayed release products : Place unbroken tablet on tongue to dissolve. What special dietary instructions should I follow? No toxic effects due to either drug were recorded. Administering with food may reduce gastrointestinal upset and 500mg discomfort caused by tinidazole but does not affect bioavailability. This is because drinking alcohol info tinidazole is likely to make you feel very sick and cause other unpleasant effects. This medicine works best when there is a constant amount in the blood. Your healthcare professionals what already be aware of this interaction and may be monitoring you for it.
Should be taken with food. Take during or immediately after meals. Side Effects Reported side effects have generally been infrequent, mild and self-limiting. Side effects from the gastrointestinal tract include nausea, vomiting, anorexia, diarrhoea and metallic taste. Hypersensitivity reactions, occasionally severe, may occur in rare cases in the form of skin rash, pruritis, urticaria and angioneurotic oedema. As with related compounds, tinidazole may produce transient leukopenia. Other rarely reported side-effects are headache, tiredness, furry tongue and dark urine. Toxicity There are no reported overdoses with tinidazole in humans. Precaution Compounds of similar chemical structure have produced various neurological disturbances such as dizziness, vertigo, uncoordination, and ataxia. If, during therapy with tinidazole, abnormal neurological signs develop, therapy should be discontinued. While there is no evidence that tinidazole is harmful during the late stages of pregnancy, its use during the last two trimesters requires that the potential benefits outweigh the possible risk to mother and foetus. Tinidazole is excreted in breast milk in concentrations similar to those seen in serum. Tinidazole can be detected in breast milk for up to 72 hours following administration. Interruption of breast-feeding is recommended during tinidazole therapy and for 3 days following the last dose. Interaction The following interactions were reported with metronidazole, which is chemically-related to tinidazole. Alcohol, disulfiram: Avoid during tinidazole use and for 3 days afterward because cramps, nausea, vomiting, headaches, and flushing may occur. Anticoagulants, oral eg, warfarin : Anticoagulant effects may be increased. Anticoagulant dose may need to be adjusted during coadministration and for up to 8 days after discontinuation. Cholestyramine: Bioavailability of tinidazole may be decreased. Cyclosporine, lithium, tacrolimus: Levels may be elevated by tinidazole, increasing the risk of toxicity. Drugs that induce CYP3A4 eg, fosphenytoin, phenobarbital, phenytoin, rifampin : May increase metabolism of tinidazole, decreasing plasma levels and therapeutic effect. Oxytetracycline: Therapeutic effect of tinidazole may be decreased. Food Interaction Avoid alcohol. Avoid concomitant use of alcohol with tinidazole as it may cause flushing, nausea, vomiting, and headaches. Take with food. Administering with food may reduce gastrointestinal upset and epigastric discomfort caused by tinidazole but does not affect bioavailability. There have been a few case reports involving metronidazole, although data overall are not convincing. Can you take paracetamol and lansoprazole at the same time? You should start to feel better within 2 to 3 days. However, it may take up to 4 weeks for lansoprazole to work properly so you may still have some acid symptoms during this time. Are there any side effects to taking lansoprazole? It can also be taken by children when prescribed by a doctor. How often can you take lansoprazole for erosive esophagitis? Usual Adult Dose for Erosive Esophagitis. Treatment: 30 mg orally once a day. Maintenance: 15 mg orally once a day. Comments: -Controlled maintenance studies did not extend beyond 12 months. How often should I take the nonprescription lansoprazole? Nonprescription lansoprazole is usually taken once a day, in the morning before eating for 14 days. If needed, additional day treatments may be repeated, not more often than once every 4 months. Take lansoprazole at around the same time s every day. Follow the directions on your prescription label carefully,… When to take lansoprazole and amoxicillin at the same time? If you are taking this medicine to treat an ulcer that is associated with an H. To use the delayed-release capsule: Swallow the capsule whole. Do not break, crush, or chew it. When to take lansoprazole for gastroesophageal reflux? To treat gastroesophageal reflux disease GERD : Adults and children 12 years of age and older—15 milligrams mg once a day before a meal. Your doctor may adjust your dose as needed. Children 1 to 11 years of age and weighing 30 kg or more—30 mg once a day before a meal. Can you take lansoprazole and sucralfate at the same time? If you also take sucralfate Carafate , avoid taking it at the same time you take this medicine. Sucralfate can make it harder for your body to absorb lansoprazole. Dec 01, · Tindamax (tinidazole) is an antibiotic drug prescribed to treat bacterial vaginosis. The drug also treats certain parasitic diseases (specifically amebiasis and giardiasis) and the sexually transmitted infection trichomoniasis. 1. Ciprofloxacin: antibiotic to treat bacterial infections - NHSOther drugs that have once same active ingredients e. Squeeze the drops into your ear. It's also given by injection, but this is usually done in hospital. Therapy with Levofloxacin, USP may be initiated before results of these tests can known; once results become available, appropriate therapy should be selected. Levofloxacin also contains the following Blog ingredients: Sodium chloride; tinidazole hydroxide; hydrochloric acid qs: pH 4. It is also used in the treatment of acne vulgaris day women who are older taken 14 years of age. RTV relative tumor volume were 1. Levofloxacin with Levofloxacin, USP may be initiated before results of these tinidazole are known; once results become available, appropriate therapy should be selected. To make sure ciprofloxacin is safe for you, tell your doctor if: you have had an allergy to ciprofloxacin or any other http://www.unionoysterhouse.com/media/fine/view5.html you have had a serious side effect with ciprofloxacin or another antibiotic particularly a fluroquinolone in the past you had diarrhoea when you have taken antibiotics before you or someone in your family and an abdominal aortic aneurysm or any other problem with the aorta the large blood vessel running from the heart to the abdomen you have fast, pounding or irregular heartbeats you have a heart infection, congenital heart disease or heart valve disease you have rheumatoid arthritisBehcet's disease or a connective tissue disorder such as Marfan syndrome you have problems with your tendons you have epilepsy or another health see more that puts you at risk of seizures you have problems with your kidneys you have diabetesas ciprofloxacin might affect your blood sugars 4. All rights reserved. Combination of levofloxacin and cisplatin promoted apoptosis induction in cancer what. Bite wound infection, prophylaxis or treatment animal or human bite Based on the Infectious Diseases Society 500mg America IDSA guidelines for the tinidazole and management of skin and soft tissue infections SSTIslevofloxacin, in combination with metronidazole or here, is an effective and recommended alternative option for treatment of bite wounds, particularly in patients interactions a human bite wound who are hypersensitive to beta-lactams. Similarly, no apparent effect of theophylline on levofloxacin absorption and disposition was observed. cipro doseage for kidney infection, how long will propecia take to work, dog on lasix still coughing Levofloxacin comes as a tablet and a solution liquid to take by mouth. It is usually taken once a day. The length of your treatment depends on the type of infection you have. Your doctor will tell you how long to take levofloxacin. The tablet may be taken with or without food. Levofloxacin Interactions with Alcohol. Combined use of alcohol and levofloxacin may lead to some side effects such as disorientation, nervousness, disturbances in attention, memory loss, and. Keep taking it even if you feel better in a few days. Do not miss any doses of Levofloxacin. If you miss a dose of Levofloxacin, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once or more than 1 dose in 1 day. Ask your health care provider any questions you may have about how to use Levofloxacin. Uses of Levofloxacin in details There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it. Off Label Uses Anthrax Based on the Centers for Disease Control and Prevention CDC expert panel meetings on prevention and treatment of anthrax in adults, levofloxacin is an effective and recommended agent for treatment of cutaneous anthrax and a recommended alternative agent for systemic anthrax. Bite wound infection, prophylaxis or treatment animal or human bite Based on the Infectious Diseases Society of America IDSA guidelines for the diagnosis and management of skin and soft tissue infections SSTIs , levofloxacin, in combination with metronidazole or clindamycin, is an effective and recommended alternative option for treatment of bite wounds, particularly in patients with a human bite wound who are hypersensitive to beta-lactams. Cervicitis or urethritis due to Chlamydia trachomatis infection Based on the CDC sexually transmitted diseases treatment guidelines, levofloxacin is an effective and recommended alternative agent in the treatment of cervicitis or urethritis due to C. Diabetic foot infection Based on the IDSA guideline for diagnosis and treatment of diabetic foot infections, levofloxacin, in combination with clindamycin, is an effective and recommended treatment option for diabetic foot infections. Epididymitis, acute Based on the CDC sexually transmitted diseases treatment guidelines, levofloxacin is an effective and recommended agent in the treatment acute epididymitis most likely caused by sexually transmitted chlamydia, gonorrhea, and enteric organisms in men who practice insertive anal sex in combination with ceftriaxone or for acute epididymitis most likely caused by enteric organisms as monotherapy. Helicobacter pylori eradication Based on the American College of Gastroenterology clinical guideline for the treatment of Helicobacter pylori infection, levofloxacin is an effective and recommended component of a multiple-drug regimen for the treatment of H. Neutropenia chemotherapy-induced , antibacterial prophylaxis Data from 2 randomized, double-blind, placebo-controlled trials support the use of oral levofloxacin for prophylaxis of bacterial infections in patients receiving myelosuppressive chemotherapy. Travelers' diarrhea Based on the CDC Yellow Book, the IDSA practice guidelines for the diagnosis and management of infectious diarrhea, and the American College of Gastroenterology guideline for the diagnosis, treatment, and prevention of acute diarrheal infections in adults, levofloxacin is an effective and recommended treatment option for the management of travelers' diarrhea. Tuberculosis Based on the American Thoracic Society, CDC, and IDSA guidelines for the treatment of tuberculosis, levofloxacin is an effective and recommended alternative agent for treatment of drug-resistant tuberculosis caused by sensitive organisms or when first-line agents are intolerable. Levofloxacin description sponsored Each tablet contains levofloxacin mg as active ingredient corresponding to levofloxacin hemihydrate Levofloxacin also contains the following inactive ingredients: Sodium chloride; sodium hydroxide; hydrochloric acid qs: pH 4. Levofloxacin is a synthetic broad-spectrum antibacterial agent for oral and IV administration. Chemically, levofloxacin, a chiral fluorinated carboxyquinolone, is the pure - - S -enantiomer of the racemic drug substance ofloxacin. Levofloxacin is - - S fluoro-2,3-dihydromethyl 4-methylpiperazinyl oxo-7H-pyrido[1,2,3-de]-1,4 benzoxazinecarboxylic acid hemihydrate. Levofloxacin is a light yellowish-white to yellow-white crystal or crystalline powder. The molecule exists as a zwitterion at the pH conditions in the small intestine. The data demonstrate that from pH 0. Levofloxacin is considered soluble to freely soluble in this pH range, as defined by USP nomenclature. Above pH 5. Above pH 6. Levofloxacin has the potential to form stable coordination compounds with many metal ions. Levofloxacin dosage sponsored Dosage in Adult Patients with Normal Renal Function The usual dose of Levofloxacin, USP is mg, mg, or mg administered orally every 24 hours, as indicated by infection and described in Table 1. Careful clinical observation and appropriate laboratory studies should be performed prior to and during therapy since elimination of levofloxacin may be reduced. Table 3 shows how to adjust dose based on creatinine clearance. Crystalluria and cylindruria have been reported with quinolones. Levofloxacin interactions What other drugs will affect Levofloxacin? There are no data concerning an interaction of quinolones IV with oral antacids, sucralfate, multivitamins, didanosine or metal cations. However, no quinolone should be co-administered with any solution containing multivalent cations eg, magnesium, through the same IV line. Theophylline: No significant effect of levofloxacin on the plasma concentrations, AUC and other disposition parameters for theophylline was detected in a clinical study involving 14 healthy volunteers. Similarly, no apparent effect of theophylline on levofloxacin absorption and disposition was observed. However, concomitant administration of other quinolones with theophylline has resulted in prolonged elimination half-life, elevated serum theophylline levels and a subsequent increase in the risk of theophylline-related adverse reactions in the patient population. Therefore, theophylline levels should be closely monitored and appropriate dosage adjustments made when levofloxacin is co-administered. Adverse reactions, including seizures, may occur with or without an elevation in serum theophylline levels. Warfarin: No significant effect of levofloxacin on the Cmax, AUC and other disposition parameters for R- and S-warfarin was detected in a clinical study involving healthy volunteers. Similarly, no apparent effect of warfarin on levofloxacin absorption and disposition was observed. There have been reports during the postmarketing experience in patients that levofloxacin enhances the effects of warfarin. Elevations of the prothrombin time in the setting of concurrent warfarin and levofloxacin use have been associated with episodes of bleeding. Prothrombin time, INR or other suitable anticoagulation tests should be closely monitored if levofloxacin is administered concomitantly with warfarin. Patients should also be monitored for evidence of bleeding. Cyclosporine: No significant effect of levofloxacin on the Cmax, AUC and other disposition parameters for cyclosporine was detected in a clinical study involving healthy volunteers. However, elevated serum levels of cyclosporine have been reported in the patient population when co-administered with some other quinolones. The differences, however, are not considered to be clinically significant. Therefore, no dosage adjustment is required for levofloxacin or cyclosporine when administered concomitantly. Digoxin: No significant effect of levofloxacin on the Cmax, AUC and other disposition parameters for digoxin was detected in a clinical study involving healthy volunteers. Levofloxacin absorption and disposition kinetics were similar in the presence or absence of digoxin. Therefore, no dosage adjustment for levofloxacin or digoxin is required when administered concomitantly. Probenecid and Cimetidine: No significant effect of probenecid or cimetidine on the rate and extent of levofloxacin absorption were observed in a clinical study involving healthy volunteers. |